Many factors are known to
contribute to human lifespan. Many natural health followers carefully control
their diet to include organic choices of fruits and vegetables in their
natural, uncooked state, while remaining physically active and maintaining body
weight within a healthy range. The science of how lifestyle habits and nutrition
promote health and longevity, known as Epigenetics, has dramatically advanced
our knowledge base by providing a solid understanding of telomeres, the tiny
strands of DNA akin to a zipper that shorten with poor dietary
choices, inflammation and everyday stress.
Researchers reporting in The Journal of Nutritional Biochemistry
show that reducing oxidative stress, cellular inflammation and improving DNA
methylation pathways can extend telomere length and slow the biologic aging
clock. Specific nutrients provide the necessary building blocks to support DNA
health and extend your natural lifespan.
Targeted Nutrients and Foods Increase DNA Methylation to Maintain
Telomere Length
Genetic expression is not set in
stone, and our genes are continually under the influence of our environment,
lifestyle and dietary choices. Gene settings are made initially from our time
in the womb, based largely on the nutritional status and lifestyle of the
mother. As we age, our genes instantly read micronutrient and environmental
cues in an effort to ensure short term survival. Every morsel of food energy we
consume results in an alteration in gene expression, either promoting optimal
health or eventual illness.
The methylation pathway is
critical to maintain DNA integrity and prevent telomere shortening. Foods and
nutrients that donate methyl groups are essential to prevent genetic mutations
that result in cancer. Researchers reporting in The Journal of Nutrition found that men
with the highest levels of folate in their blood have the longest telomeres
when compared to those with the lowest levels. In addition to folate (800 mcg
each day), vitamin B12 (500 to 1000 mcg daily) and the entire B-vitamin family
are associated with longer telomeres. Sulfur-enriched proteins from nuts and
seeds are also important methyl group donors.
Zinc and Magnesium Essential to DNA Health and Anti-Aging Effects
Independent research
projects have concluded that the minerals zinc (25 to 50 mg per day) and
magnesium (400 to 800 mg each day) are necessary to accurately complete DNA
sequencing during cell replication. A lack of these cofactors leads to DNA
strand breakage, premature cell destruction and acceleration of the aging
process. Vitamin C (1 to 3 grams per day) has been shown to slow the loss of
telomeres in human vascular endothelial cells, an important element in preventing cardiovascular disease.
Vitamin E tocotrienols (400 mg per day of a full-spectrum supplement) have been
shown to restore the length of telomeres while reducing DNA damage,
making it possible for a nutrient to reverse the shortening of telomeres and
reverse an underlying cause of aging.
Stress and inflammation are two
controllable factors that independently shorten telomere length and increase cell
aging. Stress management is essential to lower the release of chemical
messengers that fuel the flames of inflammation. Additionally, researchers have
identified a host of polyphenol compounds (resveratrol, grape seed extract and
curcumin) that lower systemic inflammation, help to maintain telomere length
and extend healthy lifespan.
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