Omega-3 Fatty Acid Compound Found to Halt Cancerous Tumor Growth and Metastasis

Mainstream media sources continue to trumpet headlines about the decline in cancer rates leading many to believe that modern medicine has conquered this devastating disease through a systematic regimen of slashing, burning and poisoning. Yet nearly 1.7 million people will be diagnosed with some form of cancer this year and more than 550,000 will die from the number two killer of men, women and children. These statistics should not be surprising as millions of unsuspecting individuals continue to avoid lifestyle modifications that have been shown to dramatically lower the risk of cancer.

Omega-3 DHA Metabolite Stops Cancerous Metastasis by Halting Blood Supply to Tumors

Many people would be amazed to know that there are a host of natural nutrients that have been scientifically validated to prevent, treat and halt the metastatic spread of some of the most invasive cancer lines. Researchers from the University of California Davis Health System have found that a product resulting from a metabolized omega-3 fatty acid helps combat cancer by cutting off the supply of oxygen and nutrients that fuel tumor growth and spread of the disease. They have published their findings in the prestigious journal, Proceedings of the National Academy of Sciences.

The bioactive long-chain omega-3 fat, docosahexaenoic acid (DHA), found in its free form in fatty fish and fish oil supplements, is broken down by the body into a metabolite form known as epoxy docosapentaenoic acid (EDP). Scientists know that tumor growth is promoted by the process of blood vessel formation called angiogenesis, and determined that by inhibiting this growth pattern, EDP reduces the growth and metastatic spread of tumors in a mouse model. This research provides the first scientific evidence about EDP’s potent anti-cancer, anti-metastatic effects.

Eat Fish Regularly or Supplement Daily with a Quality DHA Fish Oil Product to Halt Cancer Cell Growth

Lead study author, Dr. Guodong Zhang commented “Our investigation opens up a new understanding of the pathways by which omega-3 fatty acids exert their biologic effects… as far as we know, EDPs are the first signaling lipids that have been discovered to have such potent anti-cancer effects.” Researchers found that as EDP’s are broken down through normal body enzymatic metabolism, the metabolites of these lipids can act to suppress the growth of new blood vessels that are necessary to feed tumor growth.

The researchers also found that an imbalance of omega-6 fats to omega-3 fats that occurs in a diet high in sunflower and corn oils produces a metabolite known as arachidonic acid (ARA) that has the opposite effect of EDP. ARA increases angiogenesis and tumor progression and is a primary dietary cause of cancer development and metastasis. The study team concluded “Our results designate EDP as a unique mediator of an angiogenic switch to regulate tumorigenesis.” Additionally the scientists have established a firm link between omega-6 and omega-3 fat ratios in the development of cancer. Nutrition experts recommend 1,200 to 2,400 mg of EPA/DHA from a distilled fish oil supplement to lower the risk from cardiovascular disease and cancer progression.

Low Levels of Omega-3 Fats Accelerate Brain Aging and Dementia

Omega-3 fats including DHA and EPA are preferentially selected by the human body to form the critical cellular membrane boundary separating the cell nucleus and DNA with the surrounding extracellular environment. The precise fatty acid composition of the membrane determines permeability properties for the passage of essential materials such as oxygen, micronutrients and glucose required for proper cell function.

Researchers publishing in Neurology, the medical journal of the American Academy of Neurology, have found that a diet lacking in omega-3 fatty acids may cause your brain to age faster and lose some of its memory and cognitive capabilities. Regular fatty fish consumption or supplementing with a molecularly distilled form of fish oil is shown to improve memory and thought retention and may significantly lower the risk of cognitive decline associated with the progression of Alzheimer’s disease.

Low Blood Levels of Omega-3 Fats Impact Cognition and Learning Processes

An extensive volume of research over the past decade has demonstrated that eating fish several times each week or supplementing with fish oil standardized to provide equivalent  concentrations of the long chain fats, EPA and DHA improves brain development and improved levels of cognition as we age. Dr. Zaldy Tan of the Easton Center for Alzheimer's Disease Research at the University of California in Los Angeles noted “People with lower blood levels of omega-3 fatty acids had lower brain volumes that were equivalent to about two years of structural brain aging.”

Researchers assembled 1,575 individuals with an average age of 67 who were deemed free of dementia. The participants were given an MRI brain scan and took tests that measured mental function, body mass index (BMI) and the omega-3 fatty acid levels in their red blood cells. Scientists determined that those people in the lowest quartile of red blood cell DHA saturation had lower brain volume compared to people who had higher DHA levels. They also scored lower on tests of visual memory and executive function.

Eat Fatty Fish or Supplement with DHA Daily to Prevent Cognitive Decline

Dr. Tan and his team found a direct correlation between circulating levels of omega-3 fats and performing everyday tasks such as problem solving, multi-tasking and abstract thinking. The study team concluded “Lower RBC (red blood cell) DHA levels are associated with smaller brain volumes and a ‘vascular’ pattern of cognitive impairment even in persons free of clinical dementia.”

Nutrition experts recommend eating fatty fish at least three times per week to obtain adequate levels of the pre-formed omega-3 fats, DHA and EPA. Alternatively, you can supplement with distilled fish oil gel-caps providing between 1,200 and 2,400 mg of EPA/DHA fats (higher amounts indicated for optimal cardiovascular and brain health protection) to reduce the effects of brain aging and maintain normal brain volume as you age.

Omega-3 Fat, DHA Boosts Brain Metabolism to Lower Alzheimer’s Disease Risk

Several recently published articles highlight the critical importance of Omega-3 fats from fatty fish consumption and fish oil supplements. Scientists publishing in the journal Stroke demonstrate that the active DHA Omega-3 fat component helps brain cells to better withstand the stress load placed on the aging brain to lower the risk of a life-altering stroke by as much as a quarter.

Researchers from the Rhode Island Hospital`s Alzheimer`s Disease and Memory Disorders Center have found that DHA from supplements alter the critical brain chemistry and structure to prevent cognitive decline and abnormal brain aging. A wealth of scientific evidence is mounting to document the importance of Omega-3 fats to assist metabolic disorders that lead to dementia, stroke and chronic disease.

DHA, Omega-3 Fat Lowers Brain Inflammation to Improve Cognitive Function

Inflammation of the vital nerves and critical structures of the brain is a precursor to stress that can play an important role in the development of a life-altering stroke. Researchers publish the result of their work designed to determine if Omega-3 fatty acids from fish oil, specifically the long-chain DHA component would be sufficient to reduce neural inflammation and lower risk from a stroke.

To conduct the study, mice were broken into three groups. The first group was supplemented with a DHA-enriched diet, the second group consumed a DHA-depleted diet and the final mice were fed a control diet. After a period of three months, scientists found that only the group with the DHA-enriched diet experienced lower levels of neuroinflammation and had 25% less tissue injury following an induced stroke. They also noted that long-term supplementation resulted in a healthy buildup of DHA fat in brain tissue resulting in an enhanced Omega-3 to Omega-6 fatty acid ratio.

Consumption of Omega-3 Fats Protects the Brain to Lower Damage from a Stroke

Lead author on the study, Dr. Jasna Kriz concluded “This is the first convincing demonstration of the powerful anti-inflammatory effect of DHA Docosahexaenoic acid Essential Omega 3 fatty acid integral to the health of all cell membranes, nerve and brain function. The consumption of omega-3s creates an anti-inflammatory and neuroprotective environment in the brain that mitigates damage following a stroke.”

Additional evidence of the importance of Omega-3 fats from fish consumption or supplementation is provided by researchers from Rhode Island Hospital. A study was designed using 819 senior participants broken into three groups, those with normal cognition, mild cognitive impairment, and Alzheimer`s Disease. 117 individuals were taking fish oil supplements during the three year course of the study. Taking fish oil supplements was associated with less brain shrinkage and improved cognitive function during the study period.

The lead author, Dr. Lori Daiello concludes, “In the imaging analyses for the entire study population, we found a significant positive association between fish oil supplement use and average brain volumes in two critical areas utilized in memory and thinking.” DHA is preferentially conserved for the construction of neural structures and should be an essential part of your regular menu (from fatty fish) or as a molecularly distilled and purified supplement (500 mg to 1 gram per day) to lower stroke risk and prevent cognitive decline.

DHA Omega-3 Fat Protects Arteries, Heart and Can Prevent Blindness

As the population of American baby boomers continues to swell, age related afflictions including diabetes, cardiovascular disease and complications such as blindness are growing at a similar pace. The number of people aged 65 or older will double over the next 20 years creating an epidemic of chronic conditions that perpetuate with age.

According to the result of a study published in the American Journal of Clinical Nutrition, a diet supplemented with the Omega-3 fatty acid DHA (Docosahexaenoic acid) can significantly lower the risk of sudden cardiac death, heart disease and visual degeneration leading to blindness.

Omega-3 Fats Provide Critical Protection Against Heart Attack

Many scientific studies have proven the importance of Omega-3 fish oils in the prevention of cardiac disorders and specifically lowering the risk of sudden death from a heart attack. Research conducted by the Division of Cardiology and Department of Medicine at the University of Maryland found that the DHA fraction of fish oil dramatically alters the mitochondria in the heart muscle increasing healthy heart energy production. Researchers found that DHA activates the gene PPAR to help prevent the increasing incidence of heart failure and risk from a deadly heart attack.

Another key component in the progression of cardiovascular disease is systemic inflammation that leads to unstable plaque known to rupture and cause a heart attack. Further evidence of the importance of DHA in lowering heart diseases risk is published in the journal Nature Chemical Biology. Researchers found that DHA influences the action of immune system macrophages. Working at the genetic level, DHA is shown to control the release of cellular antioxidants that inhibit the damage caused by excessive and chronic inflammation to the coronary arteries.

DHA Fat Dramatically Lowers Risk of a Fatal Stroke

DHA is an important tool in the prevention of stroke. Many of the mechanisms that increase incidence of a heart attack also contribute to stroke risk. DHA becomes incorporated into the cell wall structure where it stabilizes existing plaque, making it less likely to break off and cause a stroke. DHA has been shown to help blood flow easier, lower the risk for clotting and reduce blood pressure. High levels of DHA can prevent hardening and thickening of the arteries that result in vascular decay.

The journal Science Translational Medicine reports the result of research that demonstrates how DHA regulated genes that can prevent blindness. DHA is highly concentrated in the retina and can control the abnormal growth of blood vessels in the eye that cause visual degradation. By halting unnecessary growth, DHA regulates vessel formation so that healthy blood vessels form and undesirable ones do not.

Fatty fish such as salmon, mackerel, herring and trout are ideal sources of Omega-3 fats including the DHA fraction. Due to the ever-increasing problem of mercury contamination in fish, supplementation is well advised. Nutrition experts recommend a molecularly distilled, dosage-controlled supplement that supplies 250 to 500 mg of DHA (not EPA and DHA combined, read labels carefully) daily to dramatically lower the risks from heart disease, heart attack, stroke and blindness.

DHA from Fish Oil Lowers Diabetes Risk, Slows Brain Aging

Human genetics have evolved by harnessing the power of a wide variety of nutrients which have been available in our food supply for countless generations. Over the past half century many of these natural nutrients which are so essential to our health have been slowly and systematically removed from the foods we eat.

DHA is a critical Omega-3 fatty acid which our ancestors found primarily in fish which is now severely deficient in our diet, causing a dramatically increased risk from diabetes and dementia. Including this powerful nutrient through targeted supplementation can prevent these conditions and regulate the progressive decline we know as aging.

DHA Inhibits Amyloid Plaque Formation

DHA is an Omega-3 fat which is preferentially used by the body for the formation of cell membranes and is especially important to the formation and function of neurons in the brain. When our body is supplied with sufficient amounts of DHA, the fat is allowed to accumulate in the brain where it increases brain cell survival and down regulates the formation of toxic amyloid beta plaque. This action effectively lowers the risk of cognitive decline and Alzheimer`s disease.

DHA Can Prevent Cognitive Decline

The results of a study published in the Journal of Nutritional Biochemistry found that DHA can protect against brain aging by preventing the typical damage associated with memory decline. DHA is stored by the brain for use during periods of stress and toxic overload to protect brain neurons. This is critical to the formation of memories, higher learning and thought which decline with the onset of dementia. Sufficient blood levels of circulating DHA are necessary to provide reserves which can be used to repair neuronal damage before memory loss becomes evident.

DHA Lowers Systemic Inflammation

Systemic inflammation is one of the key underlying causes of diabetes and DHA has been shown to regulate the metabolic disorder which results from excess body weight. Macrophages are components of our immune system which are essential for fighting invading pathogens, and accumulate in the white adipose tissue in response to weight gain. As more weight is gained macrophage activity increases and inflammation levels rise in the body with potentially devastating effects to our internal organs and vascular system.

DHA Improves Insulin Sensitivity, Prevents Diabetes

DHA has been shown to attach to a receptor on macrophages which are present in our white fat cells and down regulate inflammatory activity to reduce levels of inflammation. Higher levels of inflammation are associated with insulin resistance which is a hallmark of the progression of diabetes. According to research published in the journal Cell, DHA is the evolutionary key to mediate inflammation while safely lowering risk from diseases ranging from diabetes and cancer to cardiovascular disease.

Extensive research has confirmed DHA as the most critical fatty acid to promote cognitive function and lower dangerous levels of inflammation throughout the body. Man has evolved on a diet which is fortified with this essential fat but our modern diet is grossly deficient leading to many common diseases. The best way to ensure sufficient levels circulating in your blood is to supplement daily with a highly concentrated form of DHA to reduce the risk of diabetes and cognitive decline.

Green Tea and Fish Oil Promote Health and Assist Weight Loss

Green tea and the Omega-3 fatty acid DHA combine to provide a powerful natural shield against certain forms of cancer, heart disease, stroke and dementia while assisting weight loss and maintenance. Both of these nutrients directly target gene sequences which have been shown to lower disease risk while increasing base metabolism to burn more calories.

Include green tea and DHA in your nutritional arsenal to prevent a wide array of potentially lethal illnesses and reach your ideal weight loss goal.

Harness the Power of Green Tea Against Cancer

The active antioxidant compound in green and white tea is Epigallocatechin gallate (EGCG) which has been shown to exert significant anti-cancer properties by fighting development and proliferation of rogue cells. EGCG works by switching off the genes responsible for cancer initiation while influencing natural cell death to prevent replication. Chemical components of green tea further help to cut off the blood supply cancer cells need to grow while lowering levels of dangerous systemic inflammation known to promote cancer as well as many other diseases.

Green Tea Boosts Metabolism

The results of a study published in the European Journal of Clinical Nutrition provide evidence that EGCG increases fat oxidation by 33% through accelerated metabolism. Green tea has also been shown to inhibit fat cell formation and improve excretion of fat from abdominal adipose tissue. This study found that fat was burned at a higher rate for 2 hours after eating and deceased rapidly after that point. The study authors recommend drinking green tea or supplementing with EGCG prior to eating for maximum benefit.

The researchers also noted that higher intake of green tea or EGCG does not necessarily translate into increased levels of fat oxidation. Fresh brew your own green tea or use low dose EGCG supplements (300 mg or less) to receive the full fat metabolism effect.

DHA Provides Support for the Heart and Brain

DHA is one of two Omega-3 fats found in fish and distilled fish oil. DHA has been shown to lower levels of inflammation, provide a thinning effect to blood platelets to prevent clotting and reduce dangerous triglycerides in the blood. These benefits all contribute to the heart health benefits of DHA as research demonstrates that supplementation can cut the risk of sudden death from a heart attack by one-third.

DHA is the preferred fat used in brain cell neurons as well as most other cells in the body. Its unique properties allow for oxygen and nutrients to easily pass through the cell wall. When this vital fat is deficient, other fats must be used which create a stiffer cell membrane leading to cellular death and disease.

DHA Prevents Fat Accumulation

DHA works by influencing genes which control blood sugar, insulin secretion and fat accumulation. This Omega-3 fat targets the bioactive white adipose cells and affects how triglycerides in the blood are either burned for fuel or allowed to be stored as fat. The results of a study published in the International Journal of Obesity demonstrate the addition of DHA and Omega-3 fats increased weight loss in a group of overweight men by 28% compared to those who didn`t supplement.

It’s no surprise that natural nutrients and supplements act to promote health and assist weight loss. Green tea and DHA fats are prime examples of an intricate mechanism evolved over generations which our body uses to support our health. Incorporate these powerful nutrients into your lifestyle for improved quality of life and longevity.