Carnosine is a naturally
occurring antioxidant and metal-chelating nutrient that is shown to minimize
the damaging effects of stress on cellular function. Research presented
in the PLoS One journal explains that
carnosine can help to drastically reduce the formation of amyloid beta protein
associated with the brain tangles seen with Alzheimer’s disease.
Our antioxidant defense system is
in a continual state of flux, being tested by external pathogens, metabolic
glycation and stress that can determine quality of health and risk for disease.
Carnosine is shown to boost and recycle existing antioxidants throughout the
body to provide a natural shield against chronic illness, and may specifically
halt the progression of deadly diseases that lead to dementia and cognitive
dysfunction.
Carnosine Supplementation Improves Cellular Energy Production to Prevent
Dementia
Researchers understand that a
crucial marker of Alzheimer’s
dementia and cognitive decline is the formation of beta-amyloid protein clumps
that inhibit the normal electrical and neurotransmitter activity required to function
optimally and form new memories. Until recently scientists have not fully
understood if the tangles were the cause or result of dementia. New evidence
exists to support the theory that amyloid plaques form as a result of a
declining ability to naturally clear the protein tangles. Neuroscientists believe
that a failure in the energy producing mitochondria where glucose is converted
to ATP is to blame.
The study included mice that have
been genetically bred to develop a form of dementia that closely resembles
Alzheimer`s disease in humans. Energy-producing mitochondria are susceptible to
the ravages of free radicals and cellular imbalances in metals like copper,
iron, and zinc that cause ultimate failure of the organelles leading to numerous
chronic diseases. Supplementing the mice with carnosine
was found to “promote a strong reduction
in the hippocampal intraneuronal accumulation of amyloid-beta and completely
rescue Alzheimer`s disease and aging-related mitochondrial dysfunctions.”
Carnosine Helps Prevent Glycation and May Provide a Treatment Option
for Alzheimer’s Disease
Carnosine is a potent antioxidant
shown to dramatically lower mitochondrial damage typically caused by stress and
glycation (protein-sugar bonds) leading to cellular dysfunction and disease. The
study authors went so far as to conclude
“Our data indicate that carnosine can be
part of a combined therapeutic approach for the treatment of AD.” This is a
powerful conclusion considering that Big Pharma has no approved cure or
effective treatment for this insidious form of dementia.
Carnosine coupled with other
natural nutrients known to be neuroprotective (grape seed extract, resveratrol,
curcumin, DHA) can lower the stress placed on critical brain structures and
provide an effective shield against development and progression of disease.
Carnosine is found most commonly in beef, pork, poultry and dairy products.
Many health-minded individuals avoid a diet centered around animal-derived
foods and supplementation (1,000 mg per day) has been found to be an effective
and bioavailable alternative.
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