Natural Compound Found in Coffee Slows Alzheimer’s Disease Progression

Researchers publishing in the Journal of Alzheimer`s Disease have discovered that a natural chemical compound found in coffee combines with caffeine to create a protective shield against the development and progression of Alzheimer`s disease. Blood levels of a protective protein complex known as GCSF, short for granulocyte-colony stimulating factor are stimulated by coffee consumption and are shown to thwart disease progress.

Health-conscious individuals will want to consider drinking several cups of java each day to dramatically lower the risk of developing Alzheimer`s disease and preserve precious memories that can be stolen as the disease progresses.

Compound Found in Coffee Beans Protects Against Cognitive Decline

Researchers used mice that are genetically predisposed to develop Alzheimer`s disease to demonstrate naturally occurring compounds in coffee are able to fight off the disease process. Prior studies confirm that caffeine alone does not protect against the memory-robbing condition, yet observational studies in humans reported that daily coffee/caffeine intake during mid-life decreases the risk of Alzheimer`s disease.

The study demonstrated that caffeine consumption is an important part of the protective nature of coffee, but another yet unidentified chemical is required to maximize the effect. No protection against Alzheimer`s disease was found with consumption of decaffeinated coffee. Lead study author, neuroscientist Dr. Chuanhai Cao commented “Caffeinated coffee provides a natural increase in blood GCSF levels”.

Coffee Consumption Shown to Increase Neuron Development

Mice that were fed a regular diet of caffeinated coffee (equivalent to 4 or 5 cups of coffee each day) showed a significant increase in GCSF compared to control animals fed decaffeinated coffee or water only. Dr. Cao found “The exact way that this occurs is not understood. There is a synergistic interaction between caffeine and some mystery component of coffee that provides this beneficial increase in blood GCSF levels.”

The study authors identified three critical ways that increased levels of the protective protein GCSF improve memory performance. GCSF encourages stem cells from the bone marrow to enter the brain and remove harmful beta-amyloid clusters that are the hallmark of disease progression. Further, GCSF helps to create new connections between brain cells and increases the number of new neurons in the brain. Any natural compound that promotes the release of this protein complex will protect against the development of Alzheimer`s disease.

Caffeinated coffee consumption is safe for the vast majority of adults. The study authors concluded “We see no reason why an inherently natural product such as coffee cannot be more beneficial and safer than medications, especially to protect against a disease that takes decades to become apparent after it starts in the brain.” Five cups of coffee each day may provide a protective shield against this devastating form of dementia.