Consuming Omega-3 Fats from Fish and Supplements Lowers Mortality by One-Third

Health researchers have known for some time that eating fish regularly provides health benefits to help protect against cardiovascular disease, stroke and overall mortality. The primary long-chain fats, DHA and EPA have been shown to improve innate immune response by stimulating the effectiveness of B cells to lower systemic inflammation. Until recently, scientists have not been able to determine the impact of omega-3 fats on risk reduction for specific diseases or decline in mortality.

Researchers from the Harvard School of Public Health and the University of Washington, publishing the results of a study in the Annals of Internal Medicine have found that older adults who have higher blood levels of omega-3 fatty acids, commonly found in fatty fish and seafood, may be able to lower their overall mortality risk by as much as 27 percent and their risk of dying from heart disease by about 35 percent. Older individuals with the highest levels of omega-3 fats in their blood lived an average of 2.2 years longer than those with lower levels.

Eating Fatty Fish or Fish Oil Supplements Dramatically Lowers Risk from a Fatal Heart Attack

The study is regarded as the first to assess how serum blood levels of DHA and EPA omega-3 fats relate to total mortality and specific causes of mortality in a general population. Study author, Dr. Dariush Mozaffarian commented “Although eating fish has long been considered part of a healthy diet, few studies have assessed blood omega-3 levels and total deaths in older adults… our findings support the importance of adequate blood omega-3 levels for cardiovascular health, and suggest that later in life these benefits could actually extend the years of remaining life.”

To conduct their study, researchers examined sixteen years of data from about 2,700 U.S. adults, aged 65 or older, who participated in the Cardiovascular Health Study. All participants were healthy at the start of the study, and during follow up each had blood drawn, underwent physical exams and diagnostic testing, and were questioned about their health status, medical history, and lifestyle. Blood samples were tested for all omega-3 components (DHA, EPA and DPA) at the study outset and during follow up.

Eat Fatty Fish Three Times a Week or Supplement Daily to Slash Hear Disease Risk Factors

After adjusting for demographic, cardiovascular, lifestyle, and dietary factors, the scientists found that all three fatty acids combined were associated with a significantly lower risk of mortality (27 percent). When broken down by type, the researchers found that high DHA blood levels were associated with a 40 percent reduction in death from coronary heart disease. EPA and DPA were most strongly linked with lowered risk for stroke death and EPA significantly reduced non-fatal heart attack risk.

The team determined that the largest benefit was increasing omega-3 fat intake from a very low level to 400 mg per day. Dr. Mozaffarian concluded “The findings suggest that the biggest bang-for-your-buck is for going from no intake to modest intake, or about two servings of fatty fish per week.” Past research studies have determined that all individuals with no risk factors for heart disease should consume fatty fish three times per week or supplement with 1,200 mg fish oil daily. Those with multiple risk factors should increase intake to 2,400 mg combined EPA/DHA daily to minimize heart disease risk and extend lifespan.

Seven Lifestyle Habits that Significantly Lower Both Cancer and Heart Disease Risk

The incidence and etiology of many forms of cancer and the development of cardiovascular disease run on a parallel course as they are both the result of lifestyle habits that are well within our control. It comes as no big surprise that scientists have created a list of seven healthy practices that can dramatically lower the risk of developing either one of these illnesses that account for more than half of all deaths in the US each year. Many of these identified lifestyle habits fall within the realm of common sense, yet millions of men, women and children fail to regularly follow more than one or two habits, placing them at considerable risk for future disease and early mortality.

Lifestyle modifications slash chronic disease risk by lowering inflammation and improving health biometrics

A group of researchers from the Northwestern University Feinberg School of Medicine in Chicago have published the results of a study in the American Heart Association journal, Circulation that explains how following the American Heart Association's Life's Simple 7 steps to reduce your risk for heart disease can also help prevent cancer. Lead study author, Dr. Laura J. Rasmussen-Torvik said “We were gratified to know adherence to the Life's Simple 7 goals was also associated with reduced incidence of cancer… this can provide a clear, consistent message about the most important things people can do to protect their health and lower their overall risk for chronic diseases.”

The team identified the seven critical lifestyle habits that promote a healthy heart as: being physically active, keeping a healthy weight, eating a healthy diet, maintaining healthy cholesterol levels, keeping blood pressure down, regulating blood sugar levels and not smoking. To assess the impact of these habits on cancer risk, the researchers analyzed the health records of 13,253 men and women who were involved in the Atherosclerosis Risk in Communities Study, which tracked the seven risk factors and the participants’ health outcomes since 1987.

Dramatically Lower Your Risk for Developing Chronic Life-Threatening Diseases

The participants were interviewed at the outset of the study to establish how closely they followed the established heart disease lifestyle risk factors. After a period of twenty years, researchers reviewed hospital records and cancer registries and discovered that 2,880 of the participants were diagnosed with cancer of the lung, colon, rectum, prostate or breast. Scientists found that the incidence of cancer closely paralleled following fewer lifestyle habits, as compared to participants that did not develop the illness.

The team determined that people who followed six of the seven health metrics had a 51 percent lower cancer risk than the participants who did not meet any of the steps. When smoking was removed as a factor, participants who followed five to six of the health steps had a 25 percent lower cancer risk. Dr. Rasmussen-Torvik concluded “This adds to the strong body of research suggesting that it is never late to change, and that if you make changes like quitting smoking and improving your diet, you can reduce your risk for both cardiovascular disease and cancer.” Health-conscious individuals already follow the identified healthy lifestyle practices, but it certainly makes sense to ensure that each of these habits is at the core of your daily regimen to dramatically lower risk of heart disease and cancer.

Vegetarian Diet Lowers the Risk of Heart Disease by One-Third

Common sense dictates that a diet filed with fresh vegetables, fruit, nuts, seeds and legumes that eliminate excessive red and processed meats, fried foods and sugary sweets will benefit overall health as it naturally extends lifespan. Many people rely heavily on fast convenience and processed foods that are virtually void of any bioactive nutrients and actually stimulate the storage of body fat and encourage development and progression of most chronic illnesses that shorten our lives.

Vegetarian Diet Lowers Blood Pressure and Improves Blood Lipid Biomarkers to Reduce Heart Disease Risk

Researchers from the University of Oxford in the UK have published the result of a study in The American Journal of Clinical Nutrition that explains how the risk of hospitalization or death from heart disease is thirty-two percent lower in vegetarians than people who eat meat and fish. Heart disease continues to be the leading cause of death in all western societies, taking the lives of more than 700,000 men and women each year in the US alone.

In the largest study of its kind conducted in the UK, scientists compared rates of heart disease between vegetarians and non-vegetarians. Lead study author Dr. Francesca Crowe noted “Most of the difference in risk is probably caused by effects on cholesterol and blood pressure, and shows the important role of diet in the prevention of heart disease.” Researchers analyzed the diet of nearly 45,000 British and Scottish volunteers enrolled in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Thirty-four percent of the participants were vegetarian.

Eat Five to Nine daily Servings of Raw of Lightly Steamed Vegetables Every Day to Slash Heart Disease

Volunteers completed a lifestyle questionnaire detailing diet and exercise as well as other factors affecting health such as smoking and alcohol consumption. Almost 20,000 participants had their blood pressures recorded, and gave blood samples for cholesterol testing. Participants were tracked for nearly twenty years and researchers identified 1,235 cases of heart disease, which resulted in 169 deaths and 1,066 hospital diagnoses.

The study authors concluded “The results clearly show that the risk of heart disease in vegetarians is about a third lower than in comparable non-vegetarians.” Researchers found that vegetarians had lower blood pressures and cholesterol levels than non-vegetarians, which is thought to be the main reason behind their reduced risk of heart disease. The findings reinforce the idea that diet is critical to prevent heart disease. Nutrition experts recommend five to nine daily servings of fresh leafy greens and vegetables of all colors to halt chronic illnesses and lower risk from heart disease by one-third.

Reduced Magnesium Levels Predict Heart Disease Risk and Increase Mortality by Fifty Percent

Magnesium is a ubiquitous mineral that has been found in abundance in the human diet for countless generations. Over the past half century, this essential nutrient has been systematically weaned from the vast majority of leafy greens and vegetables due to poor soil conditions and the rapid rise in consumption of processed foods where any required nutrients have been removed in favor of added sugars, fats, artificial flavors and coloring.

Magnesium is required for proper electrical signaling within the heart muscle and helps stabilize a normal rhythm. Deficiency of the mineral has also been shown to increase arterial stiffness, increasing blood pressure and work load of the muscle, directly impacting cardiovascular health and mortality. Researchers from Japan, publishing the result of a study in the journal, Atherosclerosis have found that increased intakes of magnesium in the diet may reduce the risk of cardiovascular mortality by fifty percent.

Low Magnesium Intake Creates an Imbalance with Calcium Leading to Arterial Stiffness

Prior research works have determined that low magnesium levels are the best predictor of heart disease, contrary to the traditional belief that cholesterol or saturated fats play the biggest role. In a cohort of studies spanning the past forty years, scientists have found that low magnesium levels are linked with all known cardiovascular risk factors including high blood pressure, arterial plaque build-up, calcification of soft tissues, excess cholesterol levels and hardening of the arteries.

Researchers determined that decades of elevated calcium intake have not been balanced with increasing magnesium intake and consequently in the US, dietary calcium-to-magnesium ratios are increasing. Many people have been led to believe that they need to take copious amounts of supplemental calcium to maintain bone health, when in reality they are developing a homeostatic imbalance of the two minerals and dramatically increasing their risk of arterial stiffness, early cardiovascular disease and death.

Monitor Daily Magnesium Consumption and Supplement as Necessary to Improve Cardiovascular Health

Dr. Carloyn Dean, Medical Advisor of the Nutritional Magnesium Association concluded “…heart disease is still the number one killer in America in spite of over two decades of statin use. The fact that low levels of magnesium are associated with all the risk factors and symptoms of heart disease, hypertension, diabetes, high cholesterol, heart arrhythmia, angina and heart attack can no longer be ignored; the evidence is much too compelling.” The authors note that nuts and legumes are an excellent natural source of magnesium, yet many people avoid them due to the misconception that they are unhealthy due to the high fat content.

Daily requirements for magnesium are 320 mg for women and 420 mg for men, yet many people take in less than half of these minimum amounts leading to a significant deficiency over time. Health-conscious individuals will optimize their diet, or supplement with a blended magnesium formulation to assure a daily intake of 400 to 500 mg. Additionally, it may be necessary to limit or eliminate calcium supplementation to maintain proper calcium to magnesium balance and dramatically lower the risk of heart disease and early death.

Excess Calcium Doubles the Risk of Cardiovascular Death in Women

Cardiovascular disease continues to rank as the leading cause of death among men and women in western cultures. Many lifestyle factors, including processed food diet, lack of physical activity and daily stress contribute to this largely preventable disease and cause of early death. While there are many natural compounds and nutrients that help to help lower the risk of developing heart disease, taking supplemental calcium to prevent bone loss and osteoarthritis is now shown to be a significant factor that promotes the development of cardiovascular disease and advancing mortality, especially in women.

Excess Calcium Intake Disrupts Homeostatic Balance to Double Heart Disease Risk in Women

A research team from Uppsala University in Sweden has published the results of a study in the British Medical Journal that explains how high intakes of calcium (corresponding to diet and supplements) in women are associated with a higher risk of death from all causes, but cardiovascular disease in particular, compared with women with lower calcium intake. For decades, women have been advised to supplement with a daily course of calcium ranging from 1,000 to 1,500 mg to prevent bone loss. This study demonstrates how that advice may be a leading cause for the development of heart disease and early death.

Researchers studied 61,443 Swedish women over an average period of 19 years to test the association between heart disease risk and calcium intake. Data was gathered on total calcium received from both dietary and supplemental sources. The team grouped the women from the lowest mean calcium intake of 572 mg/day to the highest (2,137 mg/day). The scientist factored in lifestyle data including menopausal status, postmenopausal estrogen therapy, weight and height, smoking habits, leisure-time physical activity and educational level to help parse the results.

Women Need to Closely Monitor Calcium Intake from Food and Supplements to Lower Heart Disease Risk

Over the course of the study, 11,944 women, or 17 percent died. The team determined that 3,862 died from cardiovascular disease, 1,932 from heart disease and 1,100 from stroke. The study did not further differentiate specific diagnoses between cardiovascular disease and heart disease. The highest rates of death from all heart disease related causes were associated with a daily calcium intake higher than 1,400 mg/day or lower than 600 mg/day. Women in the top quartile that took a daily calcium supplement were found to be twice as likely to die when compared to those in the ideal range of 600 to 999 mg/day.

The researchers concluded that either high or low calcium intake can override normal homeostatic control causing changes in blood levels of calcium. Although not mentioned in this study, past work has also found that vitamin K is necessary to move excess calcium from the blood into the bones and teeth. Without this critical nutrient, calcium remains in circulation where it is easily bound with oxidized LDL cholesterol to form deadly arterial plaque. Individuals consuming a healthy diet rich in vegetables, nuts seeds and fruits should receive sufficient calcium from diet and naturally benefit from a reduced risk of cardiovascular disease, without the need for supplementation.

Resveratrol Protects against Blood Sugar Surges to Prevent Diabetes and Improve Cardiovascular Health

Allopathic practitioners and the pharmaceutical giants enjoy promoting natural compounds including resveratrol as worthless, akin to snake oil and frequently attempt to convince the public that they are wasting their money by using these supplements. Naturally, the big medical concerns make huge profits by selling a host of prescription drugs that account for more than 100,000 deaths every year, even when taken as prescribed. Not a single death has been recorded from using resveratrol, yet the health benefits are profoundly significant and repeatedly documented in peer reviewed scientific studies.

Scientists Detail how Resveratrol Prevents Damage from High Blood Glucose to Maintain Vascular Function

Researchers from China have published the results of a study in the journal, Genes and Nutrition, showing how resveratrol protects against common damage to the arteries that leads to atherosclerosis and cardiovascular dysfunction. While the scientists specifically detailed how the natural compound helps prevent complications in diabetics where fasting and post meal blood glucose can surge from three to five times normal, many health-conscious individuals can benefit from this information to protect them from arterial deterioration frequently associated with cardiovascular disease and increased heart attack risk.

Our arteries are lined with a delicate, single cell layer of tissue called the endothelium that is essential to maintain proper blood pressure and volume, and acts as a barrier to protect against metabolic byproducts floating in circulation. The endothelium is very sensitive to excess levels of glucose in the bloodstream and can become damaged and tear when sugar crystals remain in circulation for extended periods, such as occurs after a meal high in sugars and refined carbohydrates. When the endothelium is breached, micro cracks occur that accumulate foamy plaque leading to future coronary artery disease.

Supplement Daily with Resveratrol to Preserve Vascular Health and Halt AGE Formation

Scientists found that blood sugar surges caused the endothelium to become permeable, allowing oxidized LDL cholesterol, calcium and other circulating materials to become lodged inside the arterial wall. The study team determined that resveratrol stopped endothelial leaking and helped maintain proper vascular structure even under stressful conditions experienced with high blood sugar levels. Further, the researchers detailed the precise mechanism exerted by the compound to maintain the structural integrity of the arterial wall.

The team concluded that resveratrol helped prevent the most common type of arterial damage caused by poor diet and advanced aging. Advanced glycation end products (AGE’s) are formed when blood sugars and protein become bound to form useless structures that can adhere to and damage our arteries. Resveratrol (nutritionists recommend 400 mg of a standardized formulation per day) was shown to halt this damage and provides a critical nutritional intervention to prevent complications and maintain cardiovascular health in both diabetics and healthy individuals.

Strawberry and Blueberry Flavonoids Cut Heart Attack Risk in Women by One-Third

Thousands of research studies over the past decade have heralded the critical importance of eating a diet filled with flavonoids from a variety of brightly colored vegetables and fruits to help prevent and even treat many chronic illnesses. Most plants and fruits rely on flavonoid compounds for protection against the environment and to propagate and flourish. These same properties support human health by altering genetic expression and specifically targeting essential metabolic processes to ward off diseases such as cancer, dementia and the most prevalent killer of men and women, cardiovascular disease.

Anthocyanins from Eating Berries Dramatically Lowers Heart Attack Risk in a Large Sampling of Women

Researchers from the Harvard School of Public Health developed a study to analyze a specific sub-class of flavonoids, called anthocyanins, that has been shown to help dilate arteries, counter the buildup of plaque and provide other cardiovascular benefits. Publishing in the journal Circulation, the scientists found that women who ate at least three servings of blueberries and strawberries per week had significantly fewer heart attacks. Blueberries and strawberries contain high levels of anthocyanins that have shown cardiovascular benefits in past research studies.

Lead study author, Dr. Eric Rimm noted “Blueberries and strawberries can easily be incorporated into what women eat every week… this simple dietary change could have a significant impact on prevention efforts." The researchers developed a cohort of 93,600 women nurses, aged between 25 and 42 who completed dietary questionnaires every four years for a period of 18 years.

Eat Three to Five Servings of Fresh Mixed Berries Each Week to Lower Cardiovascular Disease Risk

Over the course of the study review period, 405 women experienced a heart attack. The study team found that women who consumed the most blueberries and strawberries had a 32-percent reduction in their risk of heart attack as compared to women who ate the berries once a month or less. Interestingly, the results did not change in women who otherwise ate a diet rich in other fruits and vegetables, providing solid proof that the flavonoids provided by the berries were responsible for the heart attack risk reduction benefits.

The study authors concluded “We have shown that even at an early age, eating more of these fruits may reduce risk of a heart attack later in life.” The study results were independent of other risk factors, such as age, high blood pressure, family history of heart attack, body mass, exercise, smoking, caffeine or alcohol intake. While this study was conducting using a large sampling of women, eating between 3 and 5 servings of fresh berries each week can dramatically lower heart attack risk for men and women alike.

Carnosine Protects Against Vascular Injury and Extends Lifespan

Most allopathic medical practitioners would argue that the process of aging is nothing more than a normal process whereby cells deteriorate at a predetermined rate controlled by genetically determined commands and heredity. Standing in stark opposition is a rapidly growing body of research and documented evidence to indicate that aging is a product of many varied lifestyle choices including physical activity, smoking and most importantly, the type of diet we regularly consume.

In addition to being a potent cellular antioxidant, carnosine exhibits a number of other unique capabilities that help limit glycation (the abnormal linking of proteins with glucose or lipids) to prevent injury to tissues and organ structures. These actions improve cardiovascular performance to protect against stroke, heart disease, dementia and increased susceptibility to cancer. Researchers publishing in the journal, Cellular Physiology and Biochemistry demonstrates that carnosine from supplements can help protect against a first stroke, and can significantly lower the damage caused by stroke.

Carnosine Binds with Zinc in the Brain to Prevent Abnormal Accumulation and Amyloid Tangles

Researchers have demonstrated that carnosine is particularly effective in providing multi-targeted protection to the heart and blood vessels through age-inducing processes such as oxidation, glycation, protein cross-linking, mitochondrial dysfunction, telomere shortening and heavy metal accumulation in tissues. Carnosine protects against ischemia or loss of blood flow to the heart muscle, preventing the devastating effect of reduced blood flow that leads to a heart attack.

A study team from the University of Glasgow in Scotland has released the result of their study in the journal Biochemistry to explain the importance of carnosine in the development and progression of cognitive decline and Alzheimer’s disease in aging adults. They noticed that dementia patients displayed lower levels of carnosine in their brains and spinal fluid than those of other older adults, and found that the condition results from multiple factors, virtually all of which have some connection to carnosine and its function in the brain.

Supplement Daily with Carnosine to Help Prevent Dementia, Heart Disease, Stroke and Diabetes

The researchers demonstrated that those parts of the brain that are first affected in early Alzheimer’s disease are the same in which carnosine is normally found in the highest concentrations. As carnosine levels fall with age, those brain areas become the most vulnerable to Alzheimer’s-related damage. Carnosine is known to bind with zinc in the brain, ushering them away from delicate tissues and preventing abnormal accumulation. Supplementation in known to increase blood levels and cellular saturation to halt protein cross-linking and the characteristic neurofibrillary tangles so frequently associated with the disease.

A growing number of forward-thinking scientists refer to carnosine as an “anti-aging dipeptide”, capable of defending against cardiovascular disease, stroke, diabetes, cognitive decline and dementia. Carnosine is readily available from high protein animal dietary sources including milk, eggs, cheese, beef, poultry and pork. Most health-minded individuals avoid these food sources for health and ethical reasons, and will want to supplement (500 to 1,000 mg per day) to shield against vascular disease and abnormal cellular aging.

Rutin Flavonoids Reduce Blood Clot Risk to Help Prevent Stroke and Heart Attack

The risk of thrombosis, commonly known as a blood clot, can represent a significant threat to overall health and quality of life. Clots that form and become unstable can break away, blocking blood flow to the brain or the heart muscle. The result can be a fatal heart attack, stroke or debilitating paralysis leading to diminished capacity that frequently signals a shortened life expectancy.

Rutin Can Prevent Blood Clots by Inhibiting Platelet Aggregation

There are a number of natural compounds that help to improve the structure of the vascular system including vitamin C and the amino acids lysine and proline. Researchers publishing in The Journal of Clinical Investigation describe the effect of a compound called rutin, commonly found in fruits and vegetables and sold over the counter as a dietary supplement that has been shown to inhibit the formation of blood clots in an animal model of thrombosis.

The lead study author, Dr. Robert Flaumenhaft, an investigator in the Division of Hemostasis and Thrombosis at BIDMC and Associate Professor of Medicine at Harvard Medical School commented “It's not always fully appreciated that the majority of Americans will die as the result of a blood clot in either their heart or their brain…. approximately half of all morbidity and mortality in the United States can be attributed to heart attack or stroke.” Any natural compound that is shown to prevent blood clot formation can significantly lower vascular-related mortality.

Eat Rutin or Supplement with Quercetin to Prevent Thrombus Formation

To conduct the study, researchers focused on a protein called disulfide isomerase (PDI) which is found in all cells. Past studies have shown that PDI is rapidly secreted from both platelets and endothelial cells during thrombosis when a clot forms in a blood vessel, and that inhibition of PDI could block thrombosis and prevent a fatal stroke or heart attack. The scientists therefore developed a wide-scale search for a natural agent capable of inhibiting the PDI protein and prevent vascular thrombosis.

Researchers identified quercetin-3-rutinoside (rutin), a bioflavonoid that is naturally found in many fruits, vegetables and teas including onions, apples and citrus fruits. The scientists noted that “Rutin proved to be the most potently anti-thrombotic compound that we ever tested”, as the flavonoid was shown to inhibit both platelet accumulation and fibrin generation during thrombus formation. Three to five daily servings of rutin from dietary sources or supplementing with 500 mg per day is shown to reduce platelet stickiness leading to blood clots and risk of early death from stroke and heart attack.

Resveratrol Provides Anti-Aging Benefits and Helps Prevent Heart Disease

Resveratrol has been a popular buzz word around the alternative health community for more than a decade, touted for its anti-aging properties and potent antioxidant and anti-inflammatory actions at the cellular level. Found in high concentrations most commonly in the skin of red grapes and in many red wines, resveratrol is thought to mimic the positive health benefits associated with calorie restriction by up-regulating longevity genes known as SIRT’s.

Scientists from the Harvard Medical School have published the result of their work in the journal, Cell Biology that demonstrates how resveratrol provides metabolic benefits as a result of directly influencing the expression of genes that affect longevity. This research confirms conclusively for the first time that the metabolic benefits of the red wine ingredient disappear in mice that lack the famed longevity gene SIRT1.

Resveratrol Directly Influences Genetic Expression to Increase Lifespan

Resveratrol, commonly referred to as a ‘dirty molecule’, has gained notoriety for its unique ability to influence or alter the genetic expression of the SIRT family of longevity genes. Researchers have discovered that the naturally occurring ingredient has other effects; it influences dozens of other proteins critical to essential metabolic functions, and some evidence had pointed to the importance of another well-known gene (called AMPK) for resveratrol's cellular benefits.

Researchers using a mouse model determined that resveratrol did not affect a group of mice that were genetically bred to ‘knock-out’ the SIRT gene (mice are commonly used for this type of study as they exhibit similar metabolic traits with humans). This confirmed that the grape-derived compound directly alters longevity expression in a dose dependent manner. Higher concentrations of resveratrol were found to increase the degree of genetic influence exhibited by resveratrol supplementation.

Resveratrol Lowers Systemic Inflammation to Reduce Heart Disease Risk

Further evidence documenting the importance of resveratrol to human health is provided by researchers publishing in the American Journal of Cardiology. Scientists found that cardiac patients supplemented for a period of one year with the red nutrient lowered multiple markers of inflammation (including CRP, C-reactive protein) by 26 percent, as well as reduced clotting factors associated with stroke. The researchers for this study used low doses of resveratrol (8 mg for the first six months and 16 mg for the next six months) to achieve these results.

A vocal group of naysayers constantly degrade the ever-growing evidence to support the importance of resveratrol to human wellbeing. There is little left to dispute, as researchers are regularly demonstrating that small amounts of resveratrol taken from diet or supplementation can benefit overall wellness and cardiovascular diseases by lowering levels of inflammation, providing antioxidant support and directly altering genetic expression to extend our healthy lifespan.

Soft Drink Consumption Increases Risk of Stroke and Vascular Disease

Americans drink more than 216 liters of carbonated soft drinks each year, a number that continues to increase at an alarming rate. Many people use low-calorie diet soda in a futile effort to lose weight, yet find that these drinks have the opposite effect leading to overweight or obesity. The high acid content in most carbonated beverages leaches calcium and other critical nutrients from the bone and tissues, significantly increasing disease risk over years of consumption.

Researchers from Cleveland Clinic's Wellness Institute and Harvard University have reported the result of a study in the American Journal of Clinical Nutrition, the first to examine soda's affect on stroke risk and vascular diseases. Past studies have linked sugar-sweetened beverage consumption with weight gain, diabetes, high blood pressure, high cholesterol, gout and coronary artery disease, but current research has implicated diet soft drink consumption with increased disease risk and weight gain due to depletion of essential minerals.

Carbonated beverage consumption associated with a 43% increased risk of heart attack

Lead study author Dr. Adam Bernstein noted “Soda remains the largest source of added sugar in the diet… what we're beginning to understand is that regular intake of these beverages sets off a chain reaction in the body that can potentially lead to many diseases, including stroke.” Researchers analyzed soda consumption among 43,371 men and 84,085 women over a time span of nearly thirty years. During that time, 2,938 strokes were documented in women while 1,416 strokes were documented in men.

This study emphasizes the inherent risks involved with consumption of sugar-sweetened or no-calorie soft drinks. Sweetened drinks contain high levels of glucose that lead to a rapid increase in blood glucose and insulin. Over time, this results in glucose intolerance, insulin resistance, and systemic inflammation. Low and no calorie carbonated beverages contain artificial sweeteners including aspartame, known to over stimulate and excite brain neurons resulting in cellular death.

Eliminate Soda and Substitute with Fresh Filtered Water or Brewed Green or White Tea

Further, artificial sweeteners of all types trick our digestive chemistry and hormone balance, leading to weight gain and metabolic instability. Diet soft drinks have also been shown to leach calcium from bones, as our body attempts to compensate for the high acidic load delivered from the phosphoric acid content in the drink. The end result is higher risk of osteoporosis, stroke and cardiovascular disease.

Despite the millions of dollars spent by soda marketers to instill the virtues of drinking soda, there is nothing healthy about consuming any type of carbonated beverage. Regarding low calorie drinks, researchers concluded “older adults who drank diet soda daily had a 43% increased risk of heart attack or stroke compared to those that never drank diet soda.” The study did note that drinking coffee was associated with a ten percent lower risk of stroke, compared to those drinking sweetened beverages. Substitute carbonated beverage consumption with an antioxidant packed cup of green tea or coffee to significantly reduce stroke and vascular disease risks.

Vitamin C Reduces Blood Pressure and Improves Vascular Function to Lower Heart Attack and Stroke Risk

Increased blood pressure, even before clinically diagnosed as hypertension, is a significant risk factor for cardiovascular disease and stroke. Elevations of just 3 to 5 millimeters of mercury can dramatically raise the risk of a fatal heart attack or cerebrovascular event. Nearly thirty percent of US adults have high blood pressure or hypertension that places them at much higher risk for disease progression.

Researchers from the Johns Hopkins University School of Medicine have published the result of a study showing the importance of supplemental vitamin C to lower blood pressure in the American Journal of Clinical Nutrition. Lead study author, Dr. Peter R. Miller commented “Our research suggests a modest blood pressure lowering effect with vitamin C supplementation”, noting that vitamin C taken at higher doses than suggested by the recommended daily requirement, effectively lower blood pressure enough to lower risk of a heart attack or stroke.

Vitamin C Supplementation Effectively Lowers Blood Pressure to Prevent Stroke and Heart Disease

The study involved a meta-analysis of 29 randomized, controlled and previously published clinical trials that reported systolic or diastolic blood pressure values and also compared vitamin C intake to a placebo. Many nutrition experts believe that large amounts of vitamin C, an essential micronutrient found primarily in fruits and vegetables, could lower blood pressure, but a formal study to test this hypothesis has been lacking.

The researchers found that taking an average of 500 milligrams of vitamin C daily, about five times the recommended daily requirement, reduced blood pressure by 3.84 millimeters of mercury in the short term. Among those diagnosed with hypertension, the drop was nearly 5 millimeters of mercury. While these results may not sound dramatic, they can be sufficient to dramatically lower cardiovascular and stroke risk for the millions of adults diagnosed with mild hypertension.

Eat Citrus Fruits Regularly or Supplement with Vitamin C to Lower Vascular Disease Risk

Dr. Miller concluded “Although our review found only a moderate impact on blood pressure, if the entire U.S. population lowered blood pressure by 3 milliliters of mercury, there would be a lot fewer strokes.” The team noted that the blood pressure lowering effect of vitamin C supplementation was likely due to the nutrient's biological and physiological effects. Vitamin C acts as a diuretic, causing the kidneys to remove more sodium and water from the body, which helps to relax the blood vessel walls, thereby lowering blood pressure.

Vitamin C is also known to improve essential endothelial function of delicate artery walls, effectively restoring elasticity and resolving micro-cracks in the vessels that lead to arterial plaque formation. Most nutrition experts recommend up to three grams of vitamin C supplementation per day for optimal protection from hypertension, cardiovascular disease and stroke.

Eating Tree Nuts Lowers Chronic Disease Risks and Assists Successful Weight Loss

Consumption of nuts has been largely maligned by mainstream health professionals and the media for decades due to the high calorie and fat content. As we enter an era of enlightened understanding about the role of dietary fats and macronutrients in the promotion or degradation of health and weight management, forward-thinking scientists and practitioners rely on extensive research demonstrating the importance of healthy fats in their natural state to prevent heart disease, cancer and neurodegenerative conditions.

Researchers publishing the result of their work in the Journal of the American College of Nutrition have found that eating tree nuts (almonds, Brazil nuts, cashews, hazelnuts, macadamias, pecans, pine nuts, pistachios and walnuts) was associated with higher levels of high-density lipoprotein-cholesterol (good HDL cholesterol) and lower levels of C-reactive protein, a marker for inflammation which can lead to a variety of chronic diseases including heart disease.

Tree Nuts Shown to Lower Chronic Disease Risk and Helps Prevent Obesity

Lead study author, Dr. Carol O’Neil from the Louisiana State University Agricultural Center also observed “One of the more interesting findings was the fact that tree nut consumers had lower body weight, as well as lower body mass index (BMI) and waist circumference compared to non-consumers.” The scientists determined that those consuming tree nuts as part of their regular diet averaged slightly over 4 pounds lower body weight or nearly one inch smaller waist circumference.

The study centered on a cohort of 13,292 men and women participating in the 1999-2004 National Health and Nutrition Examination Surveys. Tree nut consumers were defined as those individuals consuming more than one-quarter ounce each day as determined from 24-hour recall data and questionnaires.

Eat a Handful of Tree Nuts Each Day to Lower Chronic Disease Risk

Tree nut consumption was associated with a five percent lower incidence of metabolic syndrome, a group of risk factors known to increase the risk for coronary artery disease, stroke and type II diabetes. Researchers further noted that the nut-consuming group exhibited a lower prevalence of abdominal obesity, high blood pressure, high fasting glucose (blood sugar) levels and low high-density lipoprotein-cholesterol levels.

Tree nuts consist of largely monounsaturated fats that are known to promote heart health, and have been shown to be of critical importance for optimal brain function. Dr. O’Neil concluded “Tree nuts should be an integral part of a healthy diet and encouraged by health professionals.” Nutritionists recommend eating 1 ½ ounces each day of raw, unheated, non-salted tree nuts to lower chronic disease risk and assist weight management goals.

High Vitamin D Levels Critical to Prevent Chronic Inflammatory Diseases

The connection between cellular saturation of the prohormone, vitamin D and development of chronic conditions ranging from cancer, dementia, stroke and heart disease have been well documented among forward-thinking scientists for at least a decade now. The specific mechanism of action has not been well documented though, as most studies have not drawn a clear line between blood levels of vitamin D and disease prevention.

High Vitamin D Status Inhibits Inflammatory Messengers to Prevent Chronic Disease

Researchers from National Jewish Health reporting in The Journal of Immunology have discovered specific molecular and signaling events by which vitamin D inhibits inflammation to help prevent and possibly even treat a host of potentially deadly diseases. Current levels considered satisfactory by most medical professionals did not inhibit the inflammatory cascade, leading to the progression of many forms of disease. Conversely, individuals that maintain significantly higher blood levels of vitamin D had lower levels of inflammatory markers known to aggravate disease progression and were protected against the major killers so prevalent today.

The study author, Dr. Elena Goleva noted that this research “goes beyond previous associations of vitamin D with various health outcomes. It outlines a clear chain of cellular events, from the binding of DNA, through a specific signaling pathway, to the reduction of proteins known to trigger inflammation.” Current guidelines call for minimum vitamin D blood serum levels of 20 ng/ml, a benchmark set decades ago that was intended to prevent rickets in children and promote bone health. Researchers conducting this study found improvement in inflammation levels at a minimum of 30 ng/ml. leaving millions at risk for chronic disease.

Check Vitamin D Blood Levels Every Six Months to Prevent Inflammation

Scientists conducting this study examined the specific mechanisms exhibited by vitamin D to act on immune and inflammatory pathways. They incubated white blood cells with different saturation levels of vitamin D and then exposed the culture to an inflammatory molecule known to promote intense inflammatory responses. Cells exposed to low levels of vitamin D (less than 15 ng/ml) produced excessive levels of the inflammatory cytokines IL-6 and TNF-alpha, associated with disease development and progression. The highest level of inflammatory inhibition occurred at 50 ng/ml and above as cells become fully saturated with the prohormone and maximum immune response is observed.

Researchers identified a new location where the vitamin-D receptor appears to bind directly to DNA and activate a gene known as MKP-1, interfering with the inflammatory cascade promoted by long-term stress and a highly refined, processed food diet. Dr. Goleva concluded “The fact that we showed a dose-dependent and varying response to levels commonly found in humans also adds weight to the argument for vitamin D's role in immune and inflammatory conditions.” Maintain your vitamin D blood levels above 50 ng/ml (measured with the 25(OH)D test) to afford maximum protection against chronic inflammatory-mediated diseases.

Short Sleep Duration Significantly Decreases Heart Disease Risk

A startling number of people take a good night sleep for granted, despite the mounting body of evidence to support a restful sleep between six and eight hours every evening. In the past, studies have made a loose correlation between the numbers of hours of sleep each night and risk of diseases ranging from cancer to cardiovascular disease and dementia. Researchers from the University of Chicago are presenting the result of a study to the American College of Cardiology that explains a direct link between sleeping a minimum of six hours each night and dramatically increased risk of stroke, heart attack and congestive heart failure.

The study team found that individuals sleeping much more than eight hours each night had a significantly higher prevalence of chest pain or angina and coronary artery disease, a narrowing of the blood vessels that supply the heart with blood and oxygen. The bottom line is simple: controlling the duration of restful sleep in a totally darkened room is a modifiable risk factor that can significantly reduce risk of heart diseases and related chronic illnesses.

Sleeping Less Than Six Hours Each Night Doubles Heart Attack Risk
Researchers examined 3,019 patients, aged 45 years or older participating in the National Health and Nutrition Examination Survey, designed to assess a broad range of health issues. The study showed that people getting less than six hours of sleep each night were two times more likely to have a stroke or heart attack and 1.6 times more likely to have congestive heart failure. Conversely, those individuals that slept more than eight hours a night were two times more likely to have angina and 1.1 times more likely to have coronary artery disease.

Clearly the duration and quality of sleep is an identifiable risk factor for heart disease, robbing your health in a similar manner to poor dietary choices and lack of physical activity. The principal study investigator, Dr. Rohit Arora commented “We now have an indication that sleep can impact heart health, and it should be a priority… based on these findings, it seems getting six to eight hours of sleep everyday probably confers the least risk for cardiovascular disease over the long term.”

Sleep Seven to Nine Hours Each Night in a Fully Darkened Room to Lower Cardiovascular Disease Risk
While this research did not directly determine how sleep duration affects heart health, past studies have implicated hyper-activation of the sympathetic nervous system, glucose intolerance, diabetes, increased cortisone levels, blood pressure, resting heart rate and inflammatory markers, all known risk factors for increased risk of cardiovascular disease. As researchers continue to determine the link between sleep and heart disease, the message is clear: ensure a restful sleep between six and eight hours each night in a fully darkened room to dramatically lower heart disease risk.

Omega-3 Fats Slash Inflammation to Fight Cancer and Heart Disease

It is a commonly accepted fact within the medical research community that systemic inflammation is a primary cause of many forms of cancer, heart disease and other chronic diseases that take the lives of millions well before their time. Poor diet, stress and lifestyle factors all contribute to inflammation that overworks body metabolism and encourages damage to the delicate vascular system that feeds our heart. Production of inflammatory chemical markers such as cytokines are accelerated over months and years of exposure that creates an environment known to encourage the spread of cancer cells and propagate cardiovascular disease.

Two independent studies published in the American Journal of Clinical Nutrition have found that supplementing Omega-3 fats lowers the release of inflammatory biomarkers that are involved in damage to cells called soluble adhesion molecules. Researchers have demonstrated that Omega-3 fats from fish oil supplements effectively lower levels of circulating adhesion molecules to decrease risk of atherosclerosis and counteract the pro-carcinogenic action of these damaging compounds produced by long-term inflammation throughout the body.

Omega-3 Fatty Acids Inhibit Adhesion Molecules to Lower Heart Disease Risk
To prepare their work, researchers conducted a meta-analysis on eighteen separate studies that examined the effect of soluble adhesion molecules (sICAM-1) and Omega-3 fats and their impact on systemic inflammatory markers in the body. The results showed that Omega-3 supplements were associated with sICAM-1 reductions in both healthy people and subjects with abnormal blood lipid levels.

The scientists commented “This finding suggests that omega-3 PUFA reduces inflammation by selectively inhibiting monocyte activation rather than endothelial activation… and supports the notion that omega-3 PUFA can be supplemented to prevent the development and progression of atherosclerosis.” The Omega fats were found to lower levels of oxidized LDL cholesterol molecules and decrease particle size, both factors known to lower cardiovascular risk. The fats were also found to inhibit platelet aggregation or clumping and resolve particle adhesion properties to allow blood to flow freely through the vascular arteries.

Eat Fish Three Times Each Week or Supplement Daily with Distilled Fish Oil
A second research study performed in France determined that Omega-3 fats lower breast and prostate cancer risk in a cohort of 408 individuals with the disease, compared to 760 healthy control subjects. The scientists found a direct correlation between cancer development and Omega-3 supplementation, again by inhibiting the expression of adhesion molecules required for cancer cells to propagate.

Oily fish is the natural food source for pre-formed DHA and EPA Omega-3 fats. Many people avoid fish due to mercury contamination and unknown harvesting methods, making supplementation with a moleculary distilled form a viable option. Plant-based Omega-3 sources such as walnuts and flax seeds do not provide a good source of the necessary pre-formed long-chain fats, and while they are very healthy foods, do not yield a reliable supply of EPA and DHA fats. Read supplement labeling for a brand yielding 1,200 to 2,400 mg each day of combined EPA/DHA Omega-3 fats to lower the risks associated with heart disease and cancer.

Vitamin E Tocotrienols Work to Halt Chronic Diseases and Extend Lifespan

The result of several new research bodies have been published that all point to the powerful effect of vitamin E tocotrienols to prevent stomach cancer, reduce fatty liver disease incidence and prevent disease mechanisms that can extend natural lifespan in humans. Over the past decade, many studies have highlighted the importance of the most common vitamin E isomer known as alpha-tocopherol. While this form of the vitamin is important to lower risk of heart disease, a plethora of new evidential studies have come forth recently to show that all four of the tocotrienols must be present to provide maximum protection against illness and extend healthy lifespan.

A growing body of evidence suggests that tocotrienols possess potent biological activity and accumulate in body tissues to affect disease initiation and progression at a preferential rate compared to the mirror-image tocopherols. Researchers publishing in the Journal of Nutrition explain that vitamin E tocotrienols accumulate at elevated levels in adipose tissue, the brain, heart, and liver to help prevent over weight and obesity, dementia, cardiovascular disease and fatty liver.

Vitamin E Tocotrienols Help Prevent Stroke and Extend Cellular Life Cycle

Researchers examined blood and skin samples from 80 individuals, some healthy and others in poor health. Using high performance liquid chromatography, the scientists were able to measure the degree of vitamin E tocotrienol absorption into different organs after oral supplementation. They found that critical metabolic organ structures including fat tissue, heart, liver and brain selectively concentrated both the alpha and gamma forms of the vitamin.

This is an important finding, as the alpha isomer of vitamin E crosses the blood-brain barrier at levels that have been shown to offer neuroprotective benefits and help prevent the occurrence of stroke. The gamma form provides a protective shield to the heart muscle and can aid liver health by preventing fatty liver disease and liver cancer.

Supplement with a Full Spectrum Vitamin E Gelcap Daily to Prevent Illness

The most compelling research to date is published in the Journal of Biomedicine and Biotechnology. Scientists have demonstrated that the full spectrum of vitamin E tocotrienols yield a powerful anti-aging effect as the vitamin is shown to extend the length of telomeres while preventing damage to DNA. Telomeres are the tiny zipper-like structures that regulate cellular division and signal the end of a life cycle for each individual cell. Any mechanism that can naturally extend telomere length will slow the aging process and help prevent disease.

Vitamin E and all associated tocotrienols are readily available from a diet filled with nuts, seeds, spinach and leafy greens and certain oils such as wheat germ, sesame and olive oil. Nutrition advisors recommend consuming natural dietary sources of the vitamin daily, though some may also choose to supplement with the full spectrum of tocotrienols and tocopherols (200 – 400 mg daily spread across all isomers) to prevent chronic disease, extend telomere length and increase lifespan.