Pterostilbene is easily able to enter the cellular matrix to prevent the accumulation of advanced glycation end products (AGE's) that fuel aging and metabolic decline. Both nutrients can be obtained from a well balanced diet, but supplementation may be necessary to optimize a myriad of health benefits.
Pterostilbene is a Powerful Antioxidant that Lowers Diabetes Risk
Reporting in the Journal of Clinical Biochemistry and Nutrition, researchers found that pterostilbene was capable of assisting beta cell regranulation that helps regulate the normal secretion of insulin in response to blood sugar fluctuations. Scientists demonstrated that the compound neutralized the effect of free radicals that damage beta cells after a meal high in sugar and refined carbohydrates. This capability helped to increase insulin response and reverse the damaging effects of insulin resistance commonly seen in diabetics.
Pterostilbene Prevents Deadly Atherosclerotic Plaques
Atherosclerosis is characterized by the abnormal proliferation of cells within the endothelial lining of the coronary arteries that lead to plaque formation. Pterostilbene has been shown to inhibit this deadly process in a study published in the journal Vascular Pharmacology. Researchers found that the compound regulated DNA of the smooth muscles that make up the inner lining of the arteries so plaque was less likely to accumulate. The study authors concluded “pterostilbene may be a potential anti-proliferative agent for the treatment of atherosclerosis.”
Pterostilbene Suppresses Cancer Cell Signaling and Development
publishing in the Journal of Agricultural and Food Chemistry found that pterostilbene “damages a cancer cell`s membrane and DNA and induces death signals causing self-destruction.” The nutrient has demonstrated the ability to suppress the energy-producing system within the cancer cell to protect against cancers of the breast, prostate, colon, lung and liver.
Pterostilbene functions by affecting multiple cellular mechanisms to enhance human health and lower risk from diabetes, heart disease and cancer. Like its close relative resveratrol, this super nutrient is found in small concentrations in muscadine and red varietal grapes as well as many members of the dark berry family including blueberries and cranberries. Health-minded individuals may want to consider supplementation to obtain the higher research dosage (.125 mg) shown to prevent chronic disease and extend healthy lifespan.